Why are some people against Salmonella are protected

Not everyone who comes with Salmonella in touch, ill. In fact, it only comes in ten to twenty percent of the cases, an outbreak of the disease. Scientists at the Ludwig-Maximilians-University in Munich have found that a bacterium can protect the intestinal flora may be from infection.

The researchers have identified a gut bacteria that in animal studies protects against infections with the two most common occurring in Germany Salmonella species found in the intestine of mice, which could be due to Salmonella, not to impress, bacteria called Mucispirillum schaedleri. In the animals that were sick, lacked this kind in the intestinal flora. In further studies, the researchers showed that Mucispirillum competes with Salmonella in order to certain nutrients and prevents them from, in the intestinal cells to penetrate and do damage.

"Previously, it was believed that this bacterium in humans is not so common vorkommt", study leader Bärbel Stecher says. In the case of stool tests M. schaedleri will not often discovered, however, as these bacteria accumulate in the mucous layer of the intestine. "In studies in which the intestinal mucosa was studied, the bacteria at 50 percent of the subjects gefunden", so Stecher.

Salmonella bacteria cause gastrointestinal infections, especially in infants, small children, elderly or immune-weakened people hard. Why some people don’t get sick, although they have taken contaminated food, was not previously known. In order to examine how a healthy intestinal flora is composed, the against infections, protects, does not have the researchers compared the Microbiome in different groups of mice, one of which against Salmonella infections was protected, the other.